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Synthetic Biology Department

Bionanostructures Design Lab
A primary goal of the Bionanostructures Design Lab is to construct three-dimensional, self-assembling silica structures.

Associated Design Team Members

  • Roger Howe
  • Jay Keasling

In nature, diatoms assemble themselves by a recursive process that creates equisite fractal-like geometries. From a nanofabrication perspective, a key feature of the process is that the initial conditions in the system determine smaller scale structures.

We are investigating the role of a peptide family called silafins, which appear to play an important role in diatom structure. Our research may improve our understanding of the relationship between genetics and structure.

Short-term goals:

  • Form diatom-like silicon dioxide structures in vitro.
  • Create a parametric mathematical model of the formation physics.
  • Modify the boundary conditions to make engineered structures.

Design Labs:
  Metabolic pathways
  Genetic circuits
  Bio-nanostructures
  Enzymes
  Molecular motors
  Biomembranes

Aims

Design Team

Background

Contacts

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