Ebola Expert and ALS User Saphire Featured in ZMappTM BBC News Story
Advanced Light Source (ALS) user, Erica Ollman Saphire, of The Scripps Research Institute used the Berkeley Center for Structural Biology (Beamlines 5.0.2 and 8.2.2) and Beamlines 8.3.1 and 12.3.1 (for SAXS studies) when solving and studying structures of Ebola virus glycoprotein bound to antibodies. This work became the basis for ZMappTM, which has been used to treat two Ebola patients.
Microbial-Based Antimalaria Drug Shipped to Africa
This project, begun some 13 years ago by Associate Lab Director for Biosciences and JBEI CEO Jay Keasling, was culminated by an announcement on Tuesday that pharmaceutical company Sanofi and nonprofit health organization PATH have shipped 1.7 million treatments of semi-synthetic artemisinin.
iCLEM Featured as a “Cool School” on KPIX-TV
“Cool School,” a program aired Thursday mornings on Bay Area CBS affiliate KPIX, reports on unique educational efforts. On Thursday, August 7, the show highlighted iCLEM, the summer program for disadvantaged students sponsored by the Joint BioEnergy Institute (JBEI) and the Synthetic Biology Engineering Research Center (Synberc), with funding from DOE and NSF.
Startups Develop the Next Big Thing at Campus Labs
Inside Stanley Hall, which hosts UC Berkeley’s Department of Bioengineering and QB3 (led in Berkeley by PBD's Faculty Scientist, Susan Marqusee), a number of labs are in full swing over the summer, serving research facilities for students and faculty and incubators for innovative startups that may spearhead emerging industries.
“Imaging Life” Crosses Biological Boundaries, Introduces Integrated Bioimaging
Scientists studying the human tissues and entire living model organisms have an array of tools at their disposal to view the inner workings of our biological systems. Now Berkeley Lab’s Manfred Auer has helped put together a book that he believes is the first to include all the biological imaging techniques up to the tissue level in one place. Chapter co-authors include the Physical Biosciences Division's Paul Adams (Raman spectroscopic imaging) and Mark A. LeGros and Carolyn Larabell (soft x-ray tomography).
Intriguing DNA Editor Has a Structural Trigger
The molecular structures of two proteins from a family of genome-editing enzymes reveal how they target and cleave DNA. The results point the way to the rational design of new and improved versions of the enzymes for basic research and genetic engineering.
How Sweet It Is
JBEI researchers have developed a powerful new tool that can help advance the genetic engineering of “fuel” crops for clean, green and renewable bioenergy - an assay that enables scientists to identify and characterize the function of nucleotide sugar transporters, critical components in the biosynthesis of plant cell walls.
JBEI Hosts National Student Leadership Conference
The Joint BioEnergy Institute hosted 76 students who are taking part in a summer biotechnology program run by the National Student Leadership Conference (NSCL). Every summer the NSLC invites a select group of outstanding high school students, from the US and abroad, to participate in its fast-paced, high-level, interactive summer sessions.
The iCLEM Program: An Atypical Summer Job for Bay Area High School Students
Eight Bay Area high school students have been conducting scientific research on bioenergy as part of “iCLEM,” which stands for Introductory College Level Experience in Microbiology. This program provides a paid summer internship for high-potential, low income high school students who have finished their junior or sophomore year. Sponsored by the Joint BioEnergy Institute (JBEI) and the Synthetic Biology Engineering Research Center (Synberc), the program gets funding from the U.S. Department of Energy (DOE) and the National Science Foundation (NSF).
Postcards from the Photosynthetic Edge:
Berkeley Lab Researchers Take Femtosecond Snapshots of Photosynthetic Water Oxidation
Using the world’s most powerful x-ray laser, an international collaboration led by Berkeley Lab researchers took femtosecond “snapshots” of water oxidation in photosystem II, the only known biological system able to harness sunlight for splitting the water molecule. The results should help advance the development of artificial photosynthesis for clean, green, and renewable energy.
PBD's Scheller and Loqué Among Recipients of R&D 100 Awards
Two members of PBD and JBEI, Henrik Scheller and Dominique Loqué, are among the recipients of the 2014 R&D 100 awards. They were recognized for their Tissue-Specific Cell-Wall Engineering for Biofuels and Biomaterials, a suite of precision genetic tools that will improve crops bred for production of food, biofuels, industrial polymers, and pharmaceuticals.
Adam Arkin to be Featured on ‘Through the Wormhole’ Program
Adam Arkin, Director of the Physical Biosciences Division, will appear on the popular Science Channel program, "Through the Wormhole," on July 9th at 10 PM. The show, “Will We Become God?” looks at the scientific breakthroughs that are seemingly granting humans “divine” abilities.
New Discovery in Living Cell Signaling
Berkeley Lab researchers help find that what was believed to be noise is an important signaling factor. A breakthrough discovery into how living cells process and respond to chemical information could help advance the development of treatments for a large number of cancers and other cellular disorders that have been resistant to therapy.
Bionic Liquids from Lignin: New Results from the Joint BioEnergy Institute Pave the Way for Closed Loop Biofuel Refineries
While the powerful solvents known as ionic liquids show great promise for liberating fermentable sugars from lignocellulose and improving the economics of advanced biofuels, an even more promising candidate is on the horizon – bionic liquids. Researchers at the U.S. Department of Energy’s Joint BioEnergy Institute (JBEI) have developed “bionic liquids” from lignin and hemicellulose, two by-products of biofuel production from biorefineries.