Contact info:
Lawrence Berkeley National Laboratory
Physical Biosciences Division
One Cyclotron Road
Mailstop: 20A
Berkeley, California 94720
USA

Location: Building 20A - room 0355    
Phone: (510) 642-0557
Fax: (510) 642-8806     
Email: ENogales(at)lbl.gov

Research Emphasis
The overall research theme in my lab is the structural characterization of complex biological assemblies, their architecture, interactions with different ligands, and the regulation of their assembly and function. Our work centers around two main projects: the structural basis of microtubule dynamics and the structural organization of the human transcriptional initiation machinery. We are using electron microscopy, image analysis, homology modeling, and functional biochemical assays to gain new information on these systems and to progress towards models of how they are regulated in the cell.

Publications