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Physical Biosciences Division

Thomas Earnest
Senior Scientist

Department
Structural Proteomics Development Group

Major Initiatives
Berkeley Structural Genomics Center
Berkeley Center for Structural Biology

Contact info:
Lawrence Berkeley National Laboratory
One Cyclotron Road
Mail Stop: 6R-0121
Berkeley, California 94720
USA

Location: Building 64, Room 245
Phone: (510) 486-4603
Fax: (510) 486-5664
Email: TNEarnest@lbl.gov

Web sites:
Berkeley Structural Genomics Center

Publications

1. Khlebtsova, N., Hung, L.W., Miller, J., Moon, R.T., and Earnest, T., Structure of the PDZ domain of Dishevelled, Nature Structural Biology, submitted (1999).

2. Khlebtsova, N., Hung, L.W., Henderson, R.K., Moon, R.T., and Earnest, T.,
Crystallization and Preliminary X-ray Studies of the PDZ Domain of Dishevelled Protein, Acta Cryst. D. in press (1999).

3. Segelke, B.W., Trakhanov, S.D., Knapp, M., Parkin, S., Corzett, M., Weisgraber, K., Newhouse, Y.M., Bellamy, H.D., Earnest, T. and Rupp, B., Conformational Mobility and Helical Uncoiling in Apolipoprotein E : Re-determination of the Structure in Three New Crystal Forms Using Selenium MAD Phasing, J. Molecular Biology, submitted. (1999).

4. Cate, J.H., Yusopov, M. M., Yusopova, G. Z., Earnest, T.N., Noller, H.F., X-ray Crystal Structures of 70S Ribosome Functional Complexes. Science 285 2095-2104 (1999).

5. Ybe, J.A.., Brodsky, F.M., Hofmann, K. Lin, K., Liu, S.-H., Chen, L., Earnest, T.N., Fletterick, R.J., Hwang, P.K., "Clathrin self-assembly is regulated by a tandemly repeated superhelix," Nature 399, 371-375, 1999.

6. Cork, C., Datte, P., Druillole, F., Earnest, T., Millaud, J., Xuong, N.-H., Solid-state Photon-counting Detector for Protein Crystallography, Synchrotron Radiation News, 12, 7-12 (1999)

7. Cork, C., Padmore, H., McDermott, G., Hung, L., Henderson, K., Robinson, A., and Earnest, T. The Macromolecular Crystallography Facility at the Advanced Light Source, Synchrotron Radiation News, 11, 18-25 (1998)

8. Hunt, J.F., Earnest, T. N., Bousche, O., Kalghatgi, K., Reilly, K., Horvath, C. Rothschild, K.J., Engelman, D.M. 1997. A Biophysical Study of Integral Membrane Protein Folding. Biochemistry, 36:15156-15176.

9. Beuville, E., Beche, J., Cork, C., Douence, V., Earnest, T., Millaud, J., Nygren, D., Padmore, H., Xuong, N., Datte, P. 1997. A 16x16 pixel array detector for protein crystallography. Nuclear Instruments & Methods A 395:429-434.

10. Beuville, E., Beche, J., Cork, C., Douence, V., Earnest, T., Millaud, J., Nygren, D., Padmore, H., Xuong, N., Datte, P. 1997. Two-dimensional pixel array image sensor for protein crystallography. SPIE proceedings, 2859:85-92.

 

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