• Featured Image - Solving an Organic Semiconductor Mystery
    Solving an Organic Semiconductor Mystery
  • Featured Image - Looking to the Future Earns a Place in History
    Looking to the Future Earns a Place in History
  • Featured Image - Sweet Smell of Success: JBEI Researchers Boost Methyl Ketone Production in E. coli
    Sweet Smell of Success: JBEI Researchers Boost Methyl Ketone Production in E. coli
  • Featured Image - Berkeley Center for Structural Biology to Receive $5M from HHMI to Build a New Microfocus Crystallography Beamline
    Berkeley Center for Structural Biology to Receive $5M from HHMI to Build a New Microfocus Crystallography Beamline
  • Featured Image - Lab Partners with Campus and UCSF in BRAINseed
    Lab Partners with Campus and UCSF in BRAINseed
  • Featured Image - Berkeley Lab Makes Three Permanent Hires Through Project SEARCH
    Berkeley Lab Makes Three Permanent Hires Through Project SEARCH
  • Featured Image - Photon Speedway Puts Big Data In the Fast Lane
    Photon Speedway Puts Big Data In the Fast Lane

Latest News


Brain Receptor Structures Key to Future Therapeutics

Thursday, January 29th 2015

Multiple structures of two glutamate receptors, AMPA and NMDA, were solved by x-ray crystallography in the Berkeley Center for Structural Biology (BCSB) at the ALS by Eric Gouaux and his team from the Oregon Health & Science University’s Vollum Institute. Gouaux’s team solved the structures using BCSB Beamlines 8.2.1 and 5.0.2 and refined them using Phenix x-ray crystallography software developed by the Computational Crystallography Initiative (CCI) in PBD. These structures provide … Read More >>

Renewable Biofuels Development Requires “Renaissance Researchers”

Tuesday, January 27th 2015

PBD scientists Blake Simmons and Doug Clark were quoted in a recent Bioenergy Connection article about breaking down cell walls, a necessary step for unlocking sugars in biofuels production. The piece touches on work Clark and PBD faculty scientist, Jamie Cate, are doing with enzymes to aid in deconstruction. Read More >>

Solving an Organic Semiconductor Mystery

Friday, January 16th 2015

Naomi Ginsberg, a faculty chemist with the Physical Biosciences and Materials Sciences Divisions and the University of California Berkeley, led a team that used a unique form of microscopy to study the domain interfaces within an especially high-performing solution-processed organic semiconductor called TIPS-pentacene. She and her team discovered a cluttered jumble of randomly oriented nanocrystallites that become kinetically trapped in the interfaces during solution casting. Like debris on a highway, these nanocrystallites impede the flow of charge-carriers. Organic semiconductors are prized for light … Read More >>

Instrumentation Advances Expand the Reach of X-ray Free Electron Lasers

Monday, January 5th 2015

Femtosecond crystallography (FX) is especially suitable for studying radiation sensitive enzymes that require metals for their function, as the extremely short and bright X-ray pulses can produce a diffraction image before any atomic motions can occur in the crystal. This cutting edge method is capable of extending our capacity to study smaller, more fragile crystals and determine the catalytic structures of biologically relevant macromolecules. In conventional X-ray crystallography experiments, one crystal is mounted on a goniometer, which is then used … Read More >>

Berkeley Lab’s 2014 Highlights

Monday, January 5th 2015

Take a tour of the science, people, and events that shaped our year on an interactive timeline. Several of these contributions came from the Physical Biosciences Division, including a study that produced the first detailed look at the 3D structure of the Cas9 enzyme and how it partners with guide RNA, a breakthrough discovery of how living cells process and respond to chemical information, and the identification of microbial genes that can improve both the tolerance and the production of biogasoline in engineered strains … Read More >>